How is xxy inherited

Genetic material, or DNA, is contained in tiny structures called chromosomes found inside the body's cells. A person's biological sex is determined by the sex chromosomes: females have two X chromosomes, or XX; most males have one X chromosome and one Y chromosome, or XY.

This can cause delayed development and puberty , a smaller penis and testicles, infertility, and other symptoms. The condition that causes XXY syndrome is present at birth and can't be changed.

But educational treatments and various types of therapy physical therapy , speech therapy , behavioral and mental health counseling, and occupational therapy can help someone keep pace in school and overcome problems with shyness and social development. Kids and teens with XXY syndrome sometimes have trouble fitting in with kids their own age. Some people with 47, XXY do not have any noticeable signs or symptoms features associated with the chromosome variation.

Others may have features that range from mild to severe. Puberty and adulthood is when differences may become more clear. One of the most common features shared by males with 47, XXY is hypogonadism , which means the testes do not produce enough testosterone. Other than a small period in infancy, testosterone production is not important until puberty. Low testosterone may cause some boys with 47, XXY to have delayed or incomplete puberty, as well as may worsen concentration, mood, and behavioral problems.

For others, the low testosterone may not cause noticeable symptoms until adulthood when low sexual drive and tiredness may develop and continue to worsen with age. For some men, infertility caused by no or low sperm count may be the first detected symptom. KS is the name of a collection of features that include decreased testosterone production primary hypogonadism , small testes, enlarged breast tissue gynecomastia , tall stature, long legs, wide hips, learning disabilities, behavioral problems, and social relational problems.

KS can also be caused by other sex chromosome variations. Do you have updated information on this disease? We want to hear from you. Research Research. Clinical Research Resources ClinicalTrials. Click on the link to go to ClinicalTrials. Please note: Studies listed on the ClinicalTrials.

We strongly recommend that you talk with a trusted healthcare provider before choosing to participate in any clinical study. Patient Registry A registry supports research by collecting of information about patients that share something in common, such as being diagnosed with 47, XXY. The type of data collected can vary from registry to registry and is based on the goals and purpose of that registry.

Some registries collect contact information while others collect more detailed medical information. Learn more about registries. Organizations Organizations. Organizations Supporting this Disease. Living with XXY W. Point Loma Blvd. Do you know of an organization? Learn More Learn More.

Genetics Home Reference. Accessed Aug. About Klinefelter syndrome. National Human Genome Research Institute. Klinefelter syndrome 47,XXY. Merck Manual Professional Version. Klinefelter syndrome KS. Genetic and Rare Diseases Information Center. Bearelly P, et al. Recent advances in managing and understanding Klinefelter syndrome. Ferri FF. In: Ferri's Clinical Advisor Elsevier; Hererra Lizarazo A, et al.

Endocrine aspects of Klinefelter syndrome. Current Opinion in Endocrinology, Diabetes and Obesity. Wick MJ expert opinion. Mayo Clinic. Deng C, et al.